Description
MOTS-c, short for Mitochondrial Open Reading Frame of the 12S rRNA-c, is a 16-amino-acid mitochondrial-derived peptide involved in cellular energy and metabolic signalling research.
It has been investigated in preclinical and cellular models for its relationship to metabolic homeostasis, glucose metabolism, skeletal muscle signalling, AMPK pathway activity, exercise adaptation, and age-associated metabolic function.
Synapse Peptides MOTS-c is supplied as a high-purity lyophilised research peptide for qualified laboratory use only.
Product Details
| Field | Details |
|---|---|
| Product Name | MOTS-c |
| Synonyms | MOTS-c, Mitochondrial Open Reading Frame of the 12S rRNA-c |
| Sequence | MRWQEMGYIFYPRKLR |
| Molecular Formula | C101H152N28O22S2 |
| Molecular Weight | ~2174.6 g/mol |
| Purity | ≥98% |
| Form | Lyophilised powder |
| Grade | Research grade |
| Available Sizes | 10mg / 40mg |
| Storage Before Reconstitution | Store refrigerated at 2–8°C, protected from light and heat |
| Use | Laboratory research only |
Research Applications
MOTS-c is commonly investigated in research relating to:
- Mitochondrial function and cellular energy signalling
- Metabolic homeostasis research
- AMPK pathway studies
- Glucose metabolism and insulin sensitivity models
- Skeletal muscle metabolism research
- Exercise adaptation and cellular stress-response studies
- Age-related metabolic function and longevity research
Reconstitution
Reconstitute MOTS-c using a suitable sterile research solvent according to the requirements of the intended laboratory protocol.
Gently swirl until dissolved. Do not shake vigorously. Use appropriate aseptic handling procedures and prepare only for validated research applications.
No human or veterinary dosing guidance is provided.
Storage & Handling
Store lyophilised MOTS-c refrigerated at 2–8°C before reconstitution. Keep the vial sealed, dry, and protected from light, heat, and moisture.
Once reconstituted, store according to the validated stability requirements of the research protocol. Avoid repeated freeze-thaw cycles. For best handling, aliquot reconstituted material where appropriate.
Important Information
MOTS-c is supplied for research use only.
This product is not for human consumption, injection, ingestion, veterinary use, or clinical use. It is not intended to diagnose, treat, cure, or prevent any disease.
MOTS-c should only be handled by qualified professionals in a suitable laboratory setting. Researchers are responsible for ensuring proper handling, storage, documentation, and compliance with all applicable regulations.
Sport Compliance Notice: MOTS-c is listed on the WADA Prohibited List as a metabolic modulator/AMPK activator and is prohibited in sport. This product is not intended for athlete use or performance enhancement.
FAQs
What is MOTS-c?
MOTS-c is a 16-amino-acid mitochondrial-derived peptide studied for its role in cellular energy regulation, metabolic signalling, and mitochondrial function research.
Is MOTS-c suitable for human use?
No. Synapse Peptides MOTS-c is supplied strictly for laboratory research use only. It is not for human consumption, injection, ingestion, medical use, or veterinary use.
What does 10mg or 40mg mean?
The stated amount refers to the total quantity of lyophilised MOTS-c peptide supplied in the vial.
What form does MOTS-c come in?
MOTS-c is supplied as a lyophilised powder and requires reconstitution according to the researcher’s laboratory protocol.
How should MOTS-c be stored?
Store unreconstituted MOTS-c refrigerated at 2–8°C, protected from light, heat, and moisture. Once reconstituted, store according to validated laboratory stability requirements and avoid repeated freeze-thaw cycles.
Can athletes use MOTS-c?
No. This product is for research use only and is not intended for athletes, human use, or performance enhancement. MOTS-c is listed on the WADA Prohibited List.
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